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    Liquidyne News: News

Advanced Flow Measurement Solutions: Unveiling the BioProTT™ Clamp-On SL

In the sophisticated landscape of biotechnological research and pharmaceutical manufacturing, the accuracy and integrity of flow measurement and monitoring stand as pillars of successful operations. Introducing the BioProTT™ Clamp-On SL, a revolutionary device designed to set new standards in the precision monitoring of flow rates, particularly within the nuanced environments of laboratory suites and production facilities. This cutting-edge tool, when paired with the BioProTT™ FlowTrack SL or BioProTT™ FlowMCP, heralds a new era in reliable, non-invasive flow rate measurement for a wide array of applications.

Innovative Design for Seamless Integration

The core philosophy behind the BioProTT™ Clamp-On SL centers on ease of use and minimal disruption to existing processes. Crafted from high-quality polycarbonate adhering to USP Class VI and ADCF standards, this device showcases a molded white finish, complemented by a distinctive white pull tab for straightforward identification and operation. Its design allows for a free-floating mounting option, offering unparalleled flexibility in installation across various systems and setups.

The device's click-fastening system is a marvel of engineering, allowing for rapid attachment to flexible tubing commonly found in bioprocessing applications. This feature eliminates the cumbersome and time-consuming installation procedures associated with traditional flow measurement devices, facilitating a swift integration into both upstream and downstream processes. From chromatographies and control of upstream feed to filtration, fillings, and fill and finish processes, the BioProTT™ Clamp-On SL is equipped to handle them all with unmatched precision.

Non-Invasive Measurement: Preserving Sample Integrity

A standout feature of the BioProTT™ Clamp-On SL is its non-invasive measurement method. Leveraging the sophisticated ultrasonic transit time technique, this approach involves sending ultrasonic signals across the tube and measuring the time taken for these signals to traverse the fluid medium. This external method of measurement ensures that the medium remains untouched by the measurement device, thus preserving the integrity and viability of shear-sensitive organisms and biomolecules.

This non-invasive nature offers a significant advantage over traditional invasive methods, as it completely eliminates any potential for additional shear stress on the cells or biomolecules being processed. It is an essential consideration in biopharmaceutical manufacturing, where the integrity of the product is paramount.

Precision Engineering for Accurate Measurement

The BioProTT™ Clamp-On SL's application of the ultrasonic transit time method is not merely about avoiding sample contact; it is also about achieving high measurement accuracy. This accuracy is further enhanced through customer-specific calibrations that consider the respective process parameters, such as the type of tube, the medium and its temperature, and the maximum flow rate. Such tailored calibration ensures that the device can provide highly accurate and reliable measurements, enabling flexible solutions tailored to specific application needs.

Key Advantages and Operational Flexibility

The BioProTT™ Clamp-On SL brings together a suite of features and benefits designed to meet the rigorous demands of biopharmaceutical manufacturing:

  • Intuitive Operation: The "CLICK-PULL-TWIST" design simplifies the connection process, drastically reducing the risk of operator error.
  • Membrane Pull Tabs: These ensure the simultaneous and secure removal of membranes, maintaining sterility.
  • Robust and Reusable: Its durable construction guarantees long-term performance, and the sensor is reusable across multiple applications, easily sanitized with commonly available disinfectants.
  • Customizable Calibration: The ability to store multiple calibration tables on a single sensor adds a layer of unmatched flexibility, catering to diverse flow measurement requirements with precision.

In summary, the BioProTT™ Clamp-On SL not only exemplifies innovation in non-invasive flow measurement but also redefines the standards of accuracy, ease of use, and reliability in biopharmaceutical manufacturing processes. It stands as a testament to the advancements in single-use connection technology, providing biopharmaceutical manufacturers with the quality, flexibility, and efficiency needed to propel their operations into the future.

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