Single-use assemblies and technologies have seen wide adoption in the last decade, with almost every sterile industry-shifting at least some, if not all, of the equipment involved in their manufacturing process to a single-use alternative to traditional stainless steel. Single-use equipment decreases cross-product/batch contamination risks, increases product integrity, reduces downtime, lowers cleaning costs, decreases facility set-up expenses, provides a smaller manufacturing footprint, improves facility flexibility and adaptability.