Single-use Tangential Flow Filtration (TFF) Systems - Up to 7.7 LPM
Suitable for your purpose. Single-use, scalable tangential flow filter (TFF) systems
Agilitech single-use tangential flow filter (TFF) systems have the agility and flexibility to perform purification operations immediately after delivery. The skid's unique flexibility allows you to adapt the system to your specific application while future-proofing it to scale with your business.
The chromatography skid is either a standalone unit or integrated into a DCS/SCADA system. Our engineering experts collaborate with you to customize the system to your unique requirements--whether adding or removing inlets/outlets, analytics, filters, etc. You have unrivaled flexibility with the components of this system. Choose your preferred brand, single-use assembly or bag, or bottle recirculation container. The system will also come equipped with your choice of state-of-the-art automation and control systems, such as DeltaV, Rockwell Automation, or another platform. You have the freedom to choose.
High-tech automation and control for your
We can supply the tangential flow filter (TFF) system with a DeltaV control system. Rockwell Automation is also available. Agilitech is an authorized Rockwell System Integrator. Our experienced engineers have extensive experience with Wonderware and Inductive Automation Ignition Software. To ensure the same ease-of-use and feel across platforms, the automation is built using an ISA-88 batch-compliant framework.
Easy-to-use, intuitive control panel
Automation engineers have used years of bioprocess expertise to optimize the user interface for the TFF system control panel. They have listened carefully to end-users. We identified the most critical functions and data that operators require. The user interface brings these functions and data to the top of the screen—no more digging or endless clicking to get data.
- Brand-agnostic design
- Flexible system adapts to your unique and evolving bioprocess
- Seamless integration
- State-of-the-art automation and control
- Safe and sterile single-use technology
- Low shear pump minimizes shear during recirculation
- Choice of models
| Attribute | T125 | T250 |
| General Skid Specifications | ||
| Tubing Internal Diameter | Feed and Retentate: 0.125 in Permeate: 0.125 in Inlets: 0.125 in | Feed and Retentate: 0.25 in Permeate: 0.25 in Inlets: 0.25 in |
| Feed Flow Rate | 1-500 mL/min | 0.5-7.7 LPM |
| Tank Size | Up to 10L | Up to 50L |
| Pressure rating | 60 psi/4 bar | 60 psi/4 bar |
| Temperature Range | 2–50°C | 2-50°C |
| Humidity (non-condensing) | 10-90% | 10-90% |
| Utility Requirements* | 100-120 VAC | 100-120 VAC |
| Wetted Materials | USP <88> Class VI and animal free | USP <88> Class VI and animal free |
| Membrane Holder Capacity | 0.01 m² to 0.04 m² | 0.01m² to 2.0 m² |
| Feed and Filtrate Flow Measurement | Clamp on ultrasonic flow sensor (±3%) | Clamp on ultrasonic flow sensor (±3%) |
| Inlets | 1 product 2 buffers | 1 product 2 buffers |
| Outlet Ports | 1 Filtrate | 1 Filtrate |
| Minimum Working Volume Agitator Top Agitator Bottom Bag Sensors/Sampling | Depends on mixer selected | Depends on mixer selected |
| Hold-Up Volume (excludes filtration device) | 25 mL | 50 mL |
| Dims (W x D x H)** | 635 x 559 x 635 mm | 635 x 559 x 635 mm |
| Sensor Performance | ||
| Pressure | 0-6 psi (± 2%) 6-30 psi (± 3%) 30-60 psi (± 5%) | 0-6 psi (± 2%) 6-30 psi (± 3%) 30-60 psi (± 5%) |
| Filtrate Conductivity | 0-100 mS/cm (± 3%) | 0-100 mS/cm (± 3%) |
| Vessel Weight | 0-10 kg (± 0.3%) | 0-50 kg (± 0.3%) |
| Flow | 0-4 LPM (± 3%) | 0-8 LPM (± 3%) |
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At Liquidyne, we prioritize our commitment to quality and consistency. In 2017 we achieved ISO 9001:2015 Quality Management System certification to ensure we can repeatedly deliver consistently high-quality products and solutions. Being an ISO 9001 facility, together with our USP Class VI Testing, ASME Bioprocessing Equipment (BPE), and EHEDG certification guarantee, we have the methodologies to assure quality. We will quickly and accurately rectify any issues if any of our products are ever in non-conformance.
"Thanks so much! What a quick turn around. It is a pleasure working with Liquidyne."
Process Development Manager
"I received the cart yesterday, thanks for the fast delivery! It feels sturdy. I sat on it. It does not bounce. It is also easy to clean and wipe or wash down."
Vice President, Analytical Development and Manufacturing
"Thanks again for reacting so quickly and meeting me halfway with the element. We will be able to get installed and have things keep moving overnight with the night crew. The little things like this are always greatly appreciated when working with Liquidyne."
Chemical Engineer
“This pump cut our processing time from 3 days to 1 shift. I’m not giving this pump back. You will have to come and get it if you want it... and that won’t likely happen.”
VP Antibody Manufacturing